22. The Ladykillers, “Prof. G.H. Dorr” (2004)
Image Source: IMDb
The first collaboration between Hanks and the Coen brothers, this black comedy remake features Hanks as an odd villain in one of the strangest, yet most interesting, roles of his career. The film didn’t earn much critical success and it’s one that casual film fans probably don’t know about. But it’s Hanks unlike we’ve seen him before or since.